Jamie Gorelick is tied to the subprime meltdown because of her executive role at Fannie Mae, especially given her specific responsibilities. And beyond the personal enrichment that Gorelick enjoyed as a result, the presence of high powered Democratic appointees to Fannie Mae's board was used to help fend off efforts at oversight that could have earlier detected the problems at the company. Gorelick was one of many (and yes, we will get to them as well), but she was one of high visibility and stature.
ALSO: Gorelick's role at Fannie is certainly not the only source of her infamy. Jim Lindgren notes:
This is the same Jamie Gorelick who was Deputy Attorney General in the mid 1990s and was reported to have been the author of the Clinton Administration’s WALL against sharing intelligence data between foreign and domestic agencies. Without the policies instituted by Gorelick still in place in 2001, officials might have learned more about the 9/11 attacks before the planes hit the buildings.